h2. Dynamics {latex} $s(t)=e^{-t/T_{2}}\int P(r)e^{-i\int^{t}_{0}\omega(r,t')dt'}dr$ {latex} \\ ω(r,t') = resonant frequency P(r) = probability distribution * Coherent - when ω is not a function of r (There are no interesting dynamics) * Stationary - when ω is not a function of time (the system can be refocused by a π pulse for any time) * Incoherent - stationary and not coherent, explicitly ω is a function of r (interesting question is the distribution of ω(r) * Decoherent - when ω is a function of time and r, and the t dependence is stochastic/Marchovian (interesting dynamics: distribution of ω(r), spectral density of ω(r) * Periodic - ω is a simple function of time (interesting dynamics: distribution of ω(r) at the characteristic frequency) Periodic <PIC> Frequency that an arbitrary location will see \\ {latex} $\omega(t) = \gamma r \frac{\partial B_{z}}{\partial x} cos(\omega _{s} t + \phi)$ {latex} \\ {latex} $exp(i\int^{t}_{0}\omega(t')dt'=exp(i[\gamma \frac{\partial B_{z}/\partial x}{\omega_{s}}r sin(\omega_{s}t+\phi])$ {latex} \\ {latex} $exp^{iRsin\alpha}=\sum J_{k}(R)e^{ik\alpha}$ {latex} for one location in the sample \\ h4. Problem 1 - Show that for average over φ, we get absorptive line-shape, and for isochromat, φ in general has dispersive line-shape. Show the response in cylindrical coordinate ?? - Normal shim (x,y). If terms x^2-y^2, xy, then the sideband show up at twice Ω - Calculate the FID and the spectrum, then plot them on top of each other Nuclear Spin - Zeeman interaction - Chemical shift : ppm variation due to chemistry \-> transform as a tensor (orientation of the molecule matter) {latex}$H_{z}=\omega _{0}I_{z}${latex} , {latex}$H_{cs}=-\omega _{0}\sigma I_{z}${latex} <PIC> PAS (Principle axis system) = coordinate system that leave the molecule in diagonal ?? <MATRIX> {latex}$\sigma _{z} \sigma _{z}${latex} = secular part of the chemical shift, lead to small rotation in x-y direction <PIC> h4. Problem 2 - Show that {latex} $\sigma = \sigma_{iso} + (\frac{\sigma}{2})(3 cos^{2}\theta -1)- \frac{\delta^{eta}}{4}sin^{2}\theta(e^{i2\phi}+e^{-i2\phi})$ {latex} \\ {latex} $\sigma_{iso}=(\sigma_{xx}+\sigma_{yy}+\sigma_{zz})/3$ {latex} \\ {latex} $\delta=\frac{2}{3}\sigma_{zz}-\frac{1}{3}(\sigma_{xx}+\sigma_{yy})$ {latex} \\ {latex} $\eta=3(\sigma_{yy}-\sigma_{xx})/2(\sigma_{zz}-\sigma_{xx}-\sigma_{yy})$ {latex} \\ - Under random rapid motion spins {latex}$< \sigma > = \sigma _{iso}${latex} - When η = 0 \-> < 3cos(θ)^2 \-1 > = 0, average over sphere - η = 0 ; calculate the line-shape for static powder, η ≠ 0 ; reduce to a summation over η - Find σ(θ,φ), powder distribution of the sample <PIC> Decoherence Bloc = field that a test spin would see (every spin averagely see the same distribution of B) <PIC> average vector still pointing along y => \|Bloc> of time or ensemble = 0 <EQUATIONS> h4. Problem 3 - Find the correlation time Carl-Purcell Sequence <PIC> <EQ> h4. Problem 4 - Look at diffusive attenuation of water rotate in magnetic field gradient. (The faster you rotate it, you get closer to having the real T2 effect - Is the underly process is truly stochastic Chemical Exchange let <EQ> <PIC> h4. Problem 5 - Show plot Slow Exchange <PIC> h4. Problem 6 <EQ> - Show that by collect this terms <EQ> then do phase cycle and collect data set <EQ> Then we get pure absorptive line-shape |