Overview

Relying on miRNAs, we can measure the expression of a variety of genes associated with Alzheimer's. The implementation of such a system is eased by research into Alzheimer specific miRNA signatures and the recent publication of a circuit for taking multiple miRNA inputs to mediate a desired output. Specific output relevant to our system is under development by the treatment module, so this module will use a generic output and focus on attempting to accurately identifying the presence of factors associated with Alzheimer's, preferably in the early stage before symptoms set in.

 

 

 

Workflow

 

 

 

Circuit Diagrams


Complete Circuit Schematic

miR-30dmiR-7fmiR-125bmiR-146aL7aemiR-144miR-181crtTA
0000TRUE00FALSE
1011TRUE00FALSE
        
1111FALSE10FALSE
1111FALSE11FALSE
1111FALSE01FALSE
        
1111FALSE00TRUE


 

 

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