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  • not overselling - set the right expectations 
  • not underselling 
  • concise and to the point 
  • intro statistic slide is not engaging 
  • put in diagram showing pathways of the disease to emphasize the complexity of the disease 
  • mentioning the process of generating the project - brainstorming 
  • iap activities 
  • many students in igem stay and work on independent projects 
  • characteristics of alzheimer's: remove the bullets and enhance the graphics 
  • cite images
  • more fluid animation for BCell Receptor group 
  • make a diagram like the cancer classifier circuit for the miRNA
  • miRNA explanation should be smoother 

 

Rationale: why are we using synthetic biology to treat this problem: 

  • Alzheimer's disease has a set of very well defined characteristics that we can use as inputs for our processing circuit 
  • we are beginning to understand the molecular basis of the disease 
  • emphasize the complexity of the disease

 

Treatment: 

  • show cleavage of beta-amyloid oligomers on the diagram of beta-amyloid formation
  • detection module not membrane bound (also not like tango system) - transcription factor - treatment REDO DIAGRAM

Conclusion:

this is where we are and this is where we are going 

  • eg. we are beginning to manipulate mammalian cells and this is what we have (microscopy picture)