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Overview

Relying on miRNAs, we can measure the expression of a variety of genes associated with Alzheimer's. The implementation of such a system is eased by research into Alzheimer specific miRNA signatures and the recent publication of a circuit for taking multiple miRNA inputs to mediate a desired output. Specific output relevant to our system is under development by the treatment module, so this module will use a generic output and focus on attempting to accurately identifying the presence of factors associated with Alzheimer's, preferably in the early stage before symptoms set in.

 

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Workflow

 

 

 

Circuit Diagrams


Complete Circuit Schematic

miR-30dmiR-7fmiR-125bmiR-146aL7aemiR-144miR-181crtTA
0000TRUE00FALSE
1011TRUE00FALSE
        
1111FALSE10FALSE
1111FALSE11FALSE
1111FALSE01FALSE
        
1111FALSE00TRUE