Paper on peripheral tolerance induction - http://cshperspectives.cshlp.org/content/4/6/a006957.full#sec-8

Somewhat sketchier site but makes a clear point - http://cellular-immunity.blogspot.com/2007/12/anergy.html

      - "When T cells receive stimulus only TCR signals in the absence of engagement of costimulatory receptors, they enter a state of anergic unresponsiveness"

Paper on use of tolerogenic dendritic cells to prevent transplant rejection - http://www.nature.com/cmi/journal/v12/n1/full/cmi201452a.html

      - Suggests that they have been used experimentally in mice but not yet in humans.  The immature phenotype typically associated with Tol-DCs is apparently unstable - maybe we could fix this?

  • No labels