iGEM 2014 GOOGLE DRIVE:
https://drive.google.com/#folders/0BxtcuFzQxebWb0NXbWpwaGJSbGs
Presentation: "MITiGEM-NEGEM(3.1).pptx"
Video (Slide 3): "MITiGEM-NEGEM(3.1)-Video.m4v"
NOTES:
Include in presentation:
-Current methods of diagnosis are post-symptomatic/post-mortem. See Article on Alzheimer's Statistics: http://www.alz.org/downloads/facts_figures_2014.pdf
-Diagnostic and treatment functions can be administered separately (Human Practices)
-Variable region of antibody can be switched out and targets plaques (oligomers) specifically
-Receptor proteins target plaques (oligomers) specifically
Questions to answer:
-How to get construct into brain; delivery, crossing the BBB
-Consequences of putting gene circuit into brain
-Other effects of BACE1/BACE2 variation