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People to ContactEmailQuestionsContacted Yet?

Jacob Beal

jakebeal@bbn.com

Questions

Had first meeting

Jeremy Gam

jgam@mit.edu

QuestionsIn close contact

 

Long Term Goals

miRNA Profile

  • Read literature
  • Choose profile

Building the Cell Detector Circuit

  • Build mathematical model
  • Make test bed
    • Controlled miRNA expression
    • Constructed miRNA sensors

Mini experiments

    • Single miRNA detector circuit

Alzheimer's Model

  • Agree on a team wide, full Alzheimer's model

Today's Agenda

How To Please Ron/Brain

  • AD blood cells from PrecisionMed? Talk to Brian?
  • Meet with Kyle about designing siRNA 
    • Send order to Brian

miRNA Sensors (Theory)

  • Determine which pairs of target sites we want
    • Find sequences (hopefully under 200 bp)
    • Send ultramer order to Brian

miRNA Sensors (Lab Work)

  • Golden Gate
    • Gather miRNA target sites from Jeremy
      • Nanodrop for concentrations ( ? )
    • Make all 6 single low sensors
  • Create new and MAV vector?

NOTES

 

 

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